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Author: Admin | 2025-04-28
Based on "Antibiotic and Chemotherapy"written by Roger G. Finch Ciprofloxacin vs Azithromycin for Traveler's diarrhea Ciprofloxacin is the drug of first choice for traveler's diarrhea. However, in several regions there are high levels of resistance to fluoroquinolones among Campylobacter species and other enteropathogenic bacteria. A growing body of evidence supports the use of short-course ciprofloxacin in the treatment of traveler's diarrhea in children. Ciprofloxacin dosage for Traveler's diarrhea: 500 mg twice daily for 1-3 days. According to results of many clinical trials a single dose of antibiotic is generally effective. However, for severe diarrhea 3-days antibiotic therapy is more effective. Azithromycin is an alternative choice for the treatment of traveler's diarrhea. It is an important medication for traveler's diarrhea in areas with fluoroquinolone resistant Campylobacter species. Azithromycin is effective against Campylobacter species and the broad range of bacteria that cause traveler's diarrhea. Also, azithromycin is a suitable safe choice for children and pregnant women. Azithromycin dosage for Traveler's diarrhea: 500 mg daily for one to three days or 1,000 mg as a single dose. ShigellosisCiprofloxacin is somewhat more effective than azithromycin in the treatment of Shigellosis (a type of infective diarrhea) 3. Results of randomized, double-blind comparison of azithromycin and ciprofloxacin for shigellosis 3. Ciprofloxacin Azithromycin Regimen 500 mg every 12 hours for 5 days. 500 mg on day 1, followed by 250 mg once daily for 4 days Clinical success rate 32 (89%) patients 28 (82%) patients Bacteriologic success rate 36 (100%) patients 32 (94%) patients Ciprofloxacin vs Azithromycin for UTI Most urinary tract infections represent acute uncomplicated cystitis. E. coli is the predominant pathogen in uncomplicated UTIs. Currently, neither ciprofloxacin nor azithromycin are the first line antibiotics for UTIs. In other words, these drugs are not the best, mainly because of growing bacterial resistance to these antibiotics. Ciprofloxacin is approved by the FDA for the treatment urinary tract infections. Ciprofloxacin may be used in situations, when first line drugs (fosfomycin, nitrofurantoin, and trimethoprim/sulfamethoxazole) cannot be used. Azithromycin is not indicated for UTIs. Azithromycin may be used to treat urinary problems secondary to sexually transmitted infections. Azithromycin and ciprofloxacin
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