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Author: Admin | 2025-04-28
Can destroy the outer wall (membrane) of a cancer cell. Blocking cell growth. Some monoclonal antibodies block the connection between a cancer cell and proteins that promote cell growth — an activity that is necessary for cancer growth and survival. Preventing blood vessel growth. In order for a cancerous tumor to grow and survive, it needs a blood supply. Some monoclonal antibody drugs block protein-cell interactions necessary for the development of new blood vessels. Blocking immune system inhibitors. Your body keeps your immune system from being overactive by making proteins that control the activity of the immune system cells. Monoclonal antibodies can interfere with that process so that your immune system cells are allowed to work without controls against cancer cells. Directly attacking cancer cells. Certain monoclonal antibodies may attack the cell more directly. When some of these antibodies attach to a cell, a series of events inside the cell may cause it to self-destruct. Delivering radiation treatment. Because of a monoclonal antibody's ability to connect with a cancer cell, the antibody can be engineered as a delivery vehicle for other treatments. When a monoclonal antibody is combined with a small radioactive particle, it transports the radiation treatment directly to cancer cells and may minimize the effect of radiation on healthy cells. Delivering chemotherapy. Similarly, some monoclonal antibodies are combined with a chemotherapy drug in order to deliver the treatment directly to the cancer cells while avoiding healthy cells. Binding cancer and immune cells. Some drugs combine two monoclonal antibodies, one that attaches to a cancer cell and one that attaches to a specific immune system cell. This connection may promote immune system attacks on the cancer cells. How are monoclonal antibody drugs used in cancer treatment?Many monoclonal antibodies have been approved for treating many different types of cancer. Clinical trials are studying new drugs and new uses for existing monoclonal antibodies.Monoclonal antibodies are administered through a vein (intravenously). How often you undergo monoclonal antibody treatment depends on your cancer and the drug you're receiving. Some monoclonal antibody drugs may be used in combination with other treatments, such as chemotherapy
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