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Author: Admin | 2025-04-28
That may interact with levothyroxine:aluminum hydroxide/magnesium hydroxide (Maalox) calcium carbonate (TUMS)magnesium hydroxide/calcium carbonate (Rolaids)Steps you or your doctor may take: To avoid this interaction, you should not take antacids in the 4 hours before and 4 hours after you take your dose of levothyroxine. This allows your body enough time to absorb the full dose of levothyroxine. Learn more about levothyroxine dosages.If you have questions about taking antacids with levothyroxine, talk with your doctor or pharmacist.Proton pump inhibitorsInteraction result: Taking levothyroxine with a PPI can make levothyroxine less effective.Interaction explained: For levothyroxine to be absorbed into your body, there needs to be enough acid in your stomach. PPIs reduce the acidity in your stomach. This can prevent your body from correctly absorbing levothyroxine and lower the level of levothyroxine in your body. Having lower levels of levothyroxine can make the drug less effective in treating your condition.Examples of PPIs: Here are some PPIs that may interact with levothyroxine:esomeprazole (Nexium)omeprazole (Prilosec)pantoprazole (Protonix)Steps you or your doctor may take: If you take levothyroxine with a PPI, your doctor will likely monitor you closely to make sure levothyroxine is working for you. For example, your doctor may ask about your symptoms and order blood tests to check your thyroid hormone levels.If needed, your doctor may increase your dosage of levothyroxine or suggest that you switch to a treatment other than a PPI for your digestive condition.If you have questions about taking levothyroxine with a PPI, talk with your doctor or pharmacist.PropranololPropranolol (Inderal LA, Innopran XL) is a type of blood pressure medication known as a beta-blocker. Drugs in this class are also prescribed to treat certain heart problems, including angina (chest pain), heart failure, and irregular heart rhythm.Interaction result: Taking levothyroxine with a high dosage of propranolol — higher than 160 milligrams per day — can make propranolol less effective.Interaction explained: Propranolol works by slowing down your heart rate. Levothyroxine can increase your heart rate and oppose the effect of propranolol. This can make propranolol less effective in managing your condition.Steps you or your doctor may take: If you take levothyroxine and a high propranolol dosage, your doctor may monitor your heart rate or blood pressure more closely. If needed, they may adjust your dosage of propranolol or levothyroxine.If you have questions about taking levothyroxine and propranolol together, talk with your doctor or pharmacist.Levothyroxine may have other interactions, such as with supplements, foods, vaccines, or even lab tests. You’ll find details below. Keep in mind that the following information does not include all other possible interactions with levothyroxine.Levothyroxine interactions with supplementsBefore you start treatment with levothyroxine, tell your doctor and pharmacist which supplements, herbs, and vitamins you take. By sharing this information with them, you may help prevent possible interactions.For example, levothyroxine may interact with soy isoflavone supplements, which some people take to treat symptoms of menopause. These supplements could make levothyroxine less effective.If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.Levothyroxine and herbsThere are no
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