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Author: Admin | 2025-04-28
There are two formulations of Adderall: Adderall extended-release (XR) and Adderall immediate-release (IR). Adderall IR (dextroamphetamine/amphetamine), the immediate-release form of Adderall, is used to treat attention deficit hyperactivity disorder (ADHD) and a sleep disorder called narcolepsy. Adderall XR (mixed salts of a single-entity amphetamine product), on the other hand, is used to treat only ADHD. They both work by altering the levels of certain chemicals in the brain that help improve attention and reduce impulsiveness and hyperactivity in people with ADHD. Adderall XR and Adderall IR have the same active ingredient but differ in their formulations and how long they last. This article compares the similarities and differences between Adderall IR and Adderall XR. Getty Images / Bloomberg / Contributor Adderall XR vs. IR: What Are the Differences? Extended-release or "XR" medications release a drug slowly into the body over a period of time. Immediate-release or “IR” medications, on the other hand, release a drug into your body right away. Adderall IR is a short-acting formulation that generally lasts for about four to six hours. It is usually prescribed to be taken two to three times a day to provide symptom relief throughout the day. Adderall XR is a long-acting formulation that lasts for about 10–12 hours. It is designed to provide symptom relief throughout the day with a single dose, making it more convenient by reducing the need for multiple daily doses. The following table highlights the main similarities and differences between Adderall IR and Adderall XR. Adderall IR vs. XRAdderall IRAdderall XRUsesADHD, NarcolepsyADHDOnset of action30–45 minutes30–45 minutesDuration of action4–6 hours10–12 hoursCommon side effectsStomachache Decreased appetite NervousnessHeadacheDecreased appetiteStomachacheNervousnessTrouble sleepingMood swingsWeight lossDizzinessDry mouthFast heartbeatDosageEvery 4–6 hoursEvery day in the morningGeneric availability?YesYesStrengthsAvailable in 5 mg, 7.5mg. 10 mg. 12.5 mg, 15 mg, 20 mg, and 30 mgAvailable in 5 mg, 10 mg, 15 mg, 20 mg, 25 mg, 30 mgFormulationTabletsCapsulesHow to takeTake with or without food.Take with or without food. Swallow capsules whole with water or other liquids. If you or your child cannot swallow the capsule, open it and sprinkle the medicine over a spoonful of applesauce. Swallow without chewing immediately. Follow with a drink of water or other liquid. Dosing for Adderall XR vs. IR Adderall IR is available in tablets. Dosage recommendations for Adderall depend on the individual's age and condition:For children ages 3–5 with ADHD, a starting dose of 2.5 milligrams (mg) is recommended, with weekly increases
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