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Author: Admin | 2025-04-28
Generic name: vonoprazan fumarate 13.36mgDosage form: tabletDrug class: Proton pump inhibitorsMedically reviewed by Drugs.com. Last updated on Jul 22, 2024. Recommended DosageHealing of Erosive EsophagitisThe recommended adult oral dosage is VOQUEZNA 20 mg once daily for 8 weeks for the treatment of healing of erosive esophagitis and relief of associated heartburn.Maintenance of Healed Erosive EsophagitisThe recommended adult oral dosage is VOQUEZNA 10 mg once daily for up to 6 months for the maintenance of healed erosive esophagitis and relief of associated heartburn.Relief of Heartburn Associated with Non-Erosive Gastroesophageal Reflux DiseaseThe recommended adult oral dosage is VOQUEZNA 10 mg once daily for 4 weeks.Treatment of H. pylori InfectionTriple Therapy: The recommended adult oral dosage is VOQUEZNA 20 mg plus amoxicillin 1,000 mg plus clarithromycin 500 mg, each given twice daily (in the morning and evening, 12 hours apart) for 14 days.Dual Therapy: The recommended adult oral dose is VOQUEZNA 20 mg given twice daily (in the morning and evening) plus amoxicillin 1,000 mg three times daily (in the morning, mid-day, and evening) for 14 days.Also refer to the amoxicillin and clarithromycin full prescribing information. Recommended Dosage in Patients with Renal ImpairmentHealing of Erosive EsophagitisThe recommended dosage of VOQUEZNA in adult patients with renal impairment is described in Table 1 below.Table 1: Recommended VOQUEZNA Dosage in Patients with Renal Impairment: Healing of Erosive EsophagitisEstimated glomerular filtration rate (GFR)Recommended Dosage30 mL/minute or greater20 mg once dailyLess than 30 mL/minute10 mg once dailyMaintenance of Healed Erosive Esophagitis or Relief of Heartburn Associated with Non-Erosive Gastroesophageal Reflux DiseaseThe recommended dosage of VOQUEZNA in adult patients with renal impairment is the same as for adult patients with normal renal function.Treatment of H. pylori InfectionThe recommended dosage of VOQUEZNA in adult patients with renal impairment is described in Table 2 below.Table 2: Recommended VOQUEZNA Dosage in Patients with Renal Impairment: Treatment of H. pylori Infection*Estimated GFRRecommended Dosage*Also refer to the Dosage and Administration section of the amoxicillin and clarithromycin prescribing information for dosage recommendations in patients with renal impairment.30 mL/minute or greater20 mg twice dailyLess than 30 mL/minuteUse is not recommended Recommended Dosage in Patients with Hepatic
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